Comparing wild-type and mutant fruit flies Two different Drosophila flies (fruit
ID: 162375 • Letter: C
Question
Comparing wild-type and mutant fruit flies
Two different Drosophila flies (fruit flies), fly A and fly B, are shown below.
Classify each phrase or term as applying to fly A only, fly B only, or both fly A and fly B. The term “Hox genes” applies to clusters of homeotic genes found in many different animals, including fruit flies. After segmentation genes have established the body segments, Hox genes trigger the development of segment-specific body structures in the correct locations. For more on Hox genes, see Hints 2 and 3.
Drag each phrase or term to the appropriate bin.
head thorax abdomen antennae fly A head thorax abdomen legs fly B Adapted from Biology by Campbell and Reece 2008 Pearson Education, Inc.Explanation / Answer
Fly A only fly B only Both fly A and B possesses normal Hox genes (Reason: because all the segments of the body appear normal and Hox genes trigger development of segment-specific body structures in the correct locations) Homeotic mutant (Reason: The fly has legs instead of an antennae, this indicates presence of a mutation in the Hox genes which is a cluster of homeotic genes, hence this fly is an homeotic mutant ) Wild type (Reason: Since all the segments appear normal, the fly is a wild type strain) Exhibits abnormal pattern formation ( Reason: since this fly exhibits legs in place of antennae) Exhibits normal pattern formation (Reason:since this fly exhibits normal body morphology) possesses mutant Hox genes (Reason:since legs are seen in place of antennae in fly B and Hox genes are responsible for triggering the development of segment-specific body structures in the correct locations. Since the location of legs are wrong, it indicates a mutation in the Hox genes ) produces transcription factors triggering gene expression for segment specific structures. (Reason: Hox genes encode transcription factors. These genes are present in both flies. hence transcription factors would be present in both flies )
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