1)Collagen is constitutively secreted by fibroblast cells, which are a type of c
ID: 163154 • Letter: 1
Question
1)Collagen is constitutively secreted by fibroblast cells, which are a type of connective tissue cell. If you had a patient in which collagen is synthesized normally, but fails to be secreted into the ECM, which of the following would you examine as the likely cause of this problem?
A Ca++ deficiency
A failure of the Na+/K+ ATPase
A H+ pump disorder
None of the above
2)Which of the following most closely approximates a second messenger?
An odorant receptor on the surface of a mouse olfactory epithelium cell that undergoes a conformational change upon binding of metabolites (breakdown products) of thyroid hormones, activating an intracellular G-protein.
The enzyme cyclic GMP phosphodiesterase, which is activated when photons the light “receptor” rhodopsin in rod photoreceptors (as in rods and cones of the retina).
Na+ ions, which flow into a muscle cell in response to binding of acetylcholine to its receptor, which leads to Ca++ release from internal stores.
The neurotransmitter secreted by a neuron in response to an electrical impulse traveling down its axon when it is stimulated by another neuron.
3)Which of the following is an advantage of juxtacrine signaling?
It is fast
It affects large numbers of cells
It can be bidirectional
Two of the above are true.
4)Inhibition of which of the following would prevent indirect active transport of glucose into cells?
GluT1
Ca++ ATPase
Ligand-gated ion channels
Na+/K+ ATPase
All of the above
A Ca++ deficiency
A failure of the Na+/K+ ATPase
A H+ pump disorder
None of the above
2)Which of the following most closely approximates a second messenger?
An odorant receptor on the surface of a mouse olfactory epithelium cell that undergoes a conformational change upon binding of metabolites (breakdown products) of thyroid hormones, activating an intracellular G-protein.
The enzyme cyclic GMP phosphodiesterase, which is activated when photons the light “receptor” rhodopsin in rod photoreceptors (as in rods and cones of the retina).
Na+ ions, which flow into a muscle cell in response to binding of acetylcholine to its receptor, which leads to Ca++ release from internal stores.
The neurotransmitter secreted by a neuron in response to an electrical impulse traveling down its axon when it is stimulated by another neuron.
3)Which of the following is an advantage of juxtacrine signaling?
It is fast
It affects large numbers of cells
It can be bidirectional
Two of the above are true.
4)Inhibition of which of the following would prevent indirect active transport of glucose into cells?
GluT1
Ca++ ATPase
Ligand-gated ion channels
Na+/K+ ATPase
All of the above
Explanation / Answer
1.failure of the Na+/K+ ATPase
Na+/K+ ATPase mediate the transport of VitC and if this fails it will inhibit the collagen synthesis.
2. B
The enzyme cyclic GMP phosphodiesterase, which is activated when photons the light “receptor” rhodopsin in rod photoreceptors (as in rods and cones of the retina.
3.(C)
juxtacrine signaling has been observed for some growth factors, cytokine and chemokine cellular signals, playing an important role in the immune response.
4. (D)
Na+/K+ ATPase
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