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Some researchers argue that short telomeres actually facilitate a longer life sp

ID: 163544 • Letter: S

Question

Some researchers argue that short telomeres actually facilitate a longer life span in mammals. The reasoning for this argument includes the idea that ________.

A. The activity of telomerase expressionthe enzyme that can restore lost bits of telomeresis repressed

B. A reduction in the telomere size for every DNA replication event can serve as an accurate counting mechanism for the number of times a cell has divided

C. Reducing the number of divisions a cell will go through will also reduce the likelihood of mutation events occurring in the cell's DNA

D. All of the above are included in this idea.

Explanation / Answer

Telomeres are the caps of DNA present at the ends of chromosomes, they shorten normally as the animal ages. However, many scientists argue that there are any species with shorter lifespans that loose more telomere than species having longer lifespan. Telomerase is an important enzyme that maintains lengths of chromosomes by synthesizing telomeric sequences which are repetative or palindromic in nature. The lowering in the levels of telomerase as the age progresses ensures shorter telomeric length that reduces the frequent chances of apoptosis, hence more survival.

Therefore, the most appropriate option is: A. The activity of telomerase expressionthe enzyme that can restore lost bits of telomeresis repressed

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