I need help solving these questions. I think that is the answer but I would like

Question

I need help solving these questions. I think that is the answer but I would like to know how to solve it and why the others cannot be the answer. Thank you!

38. Phosphofructokinase-1 is a homo-tetramer. It is subject to adenylate control. It has binding sites for ATP a..1 39. Phosphofructokinase-1 can be allosterically inhibited by a. AMP. b. citrate. c. NADH. d. fructose-2,6-bisphosphate. e. ADP. 40. The cytochrome in the electron transport system that is not a transmembrane protein is: a. cytochrome-a. b. cytochrome-b. c. cytochrome-c. d. cytochrome-d.

Explanation / Answer

38. Phosphofructokinase -1 is a homo tetramer with four subunits. Each subunit has ATP binding sites, one for substrate ATP and other for inhibitor ATP. Because ATP is both a substrate and an allosteric inhibitor. So there are 8 ATP binding sites in this enzyme.

39. Citrate, phosphoenolpyuvate (PEP) and ATP act as allosteric inhibitor for this enzyme. But AMP, ADP and fructose 2,6-bisphosphate are allosteric activators.

40. Cytochrome c is not a transmembrane protein which is a small heme protein loosely associated with inner membrane of the mitochondria.

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