9. You are studying a cod population and find that two haplotypes ( A and a ) ar

Question

9. You are studying a cod population and find that two haplotypes (A and a) are common at the autosomal RAG1. The genotypes in the population are in the following numbers:

       A/A   A/a   a/a

       10   5   93

a.   What is the frequency of allele A in the population?

b.   What would Hardy-Weinberg proportions for the genotypes be?

c.   Conduct a chi-squared test on these data. Please provide your degrees of freedom and a 2 value, and please indicate whether you reject the null hypothesis at =0.05.

Explanation / Answer

(a) the frequency of A = (2*(10) + 5)/ 2* 108

=> 0.1157..

The frequency of a = (2*(93) + 5)/ 2* 108

=> 0.884..

2) Hardy weinberg states that

(p^2 +2pq+ q^2)=1

p(A) = 0.1157*0.1157 = 0.0133..

2pq = 2*0.1157*0.884 = 0.204..

q(a) = 0.884*0.884= 0.7814..

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