10. Imagine you are studying a population of water strider and have genotyped tw

Question

10. Imagine you are studying a population of water strider and have genotyped two loci. The first locus has alleles with frequencies 0.6 and 0.4 in the population. The second locus has alleles with frequencies 0.35 and 0.65. You have genotyped one young water strider at these two loci.

a.   What is the probability that we can exclude a father as the true parent (assuming that he is not the true parent)?

b.   If you could genotype a third locus to increase your probability of paternal exclusion, would you prefer a locus with allele frequencies of 0.6/04 or 0.35/0.65? Why?

c. What would your paternity exclusion power be for a single locus with three alleles of frequency 0.2, 0.2 and 0.6?

d. Is the power from part c) good enough to use for a study without adding other loci? Why or why not?

Explanation / Answer

a. The probability that we can exclude a father as the true parent 12.5%

b. If we want to genotype a third locus to increase the probability of paternal exclusion, we prefer a locus with allele frequencies of 0.6 / 0.4 because the difference between the alleles on the chromosome shows only 0.2 whereas the difference in the allelic frequency of the other locus is 0.3 .

d. No ,part c) wont be good enough to use for a study without adding other loci. Because at each loci two allele types should be present inorder to find the paternity exclusion power. So with a single locus the result can not be so accurate.

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