Peptidyl transferase activity transfers the grossing peptide chain attached to t
ID: 164637 • Letter: P
Question
Peptidyl transferase activity transfers the grossing peptide chain attached to the tRNA In the P-site to the entering tRNA containing a single amino add in the A-site. This catalytic activity is associated with which ribosomal component? C) one of the large subunit ribosomal proteins B) the small ribosomal subunit D) a ribozyme activity of the 23S ribosomal RNA A) an elongation factor E) None of the above. Proteins that are targeted to different cellular compartments other than are made on the ribosomes attached to the endoplasmic reticulum. In order for to attach to the endoplasmic reticulum, which proteins that are attached to the ribosome interact with proteins associated with the endoplasmic reticulum? E) All of the above art correct A) signal recognition D) only B) and C) are correct. C) signal peptidase B) signal recognition particle receptorExplanation / Answer
Answer 9.
The Peptidyl transfersae is an aminoacyltransferase and also acts as Ribozyme which plays an important role in the formation of peptide bond between amino acids usinf tRNA during a process known as Translation, thus involved in Protein biosynthesis. Generally, Ribozymes are enzymes which are made of ribonucleotides. Now, coming to the answer, Ribosome has two subunits - larger and smaller and indeed both the subunits are involved during Translation process.The 50S (23S component) ribosomal subunit contains peptidyl transferase component and this acts as Ribozyme in prokaryotes.
Thus, the correct answer is (D) - A ribozyme activity in 23S ribosomal RNA.
Answer 10.
The ribosome binds to Rough Endoplasmic reticulum when a specific protein nucleic acid complex is formed during the translation of mRNA process. This is followed by recognition of peptide chin by encoding Signal Peptide, which in turn is boud and recognised by Signal Recognition Particle. This causes the translation process to stop. This is followed by binding of Ribosome complex to Rough endoplasmic reticulum translocon, where translation is continued. This forms new protein in Rough endoplasmic reticulum' s lumen and/or membrane. The protein is processed in the lumen of Endoplasmic reticulum by Signal peptidase enzyme, thus removing the signal peptide.
Thus, the correct option is (E) all the above are correct.
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