David Hassenzahl discusses the relative risks of eating peanut butter contaminat
ID: 166481 • Letter: D
Question
David Hassenzahl discusses the relative risks of eating peanut butter contaminated with aflatoxin and apple juice contaminated with UDMH, a degradation product of Alar. The following Table shows his input data. The table below contains the correct information.
Variable
Units
Average
5th %ile
95th %ile
Distribution
Peanut butter intake
g/day
11.38
2.00
31.86
Lognormal
Apple juice intake
g/day
136.84
16.02
430.02
Lognormal
Aflatoxin concentration
ug/kg
2.82
1.00
6.5
Lognormal
UDMH concentration
ug/kg
13.75
0.5
42.00
Lognormal
Aflatoxin potency
kg-day/mg
17.5
4.02
28.33
Normal
UDMH potency
kg-day/mg
0.49
0.00
0.85
Normal
calculate the daily cancer risk for a child who weighs 20 kg and who eats an average amount of peanut butter. Please use the average values for the required parameters.
Do the same for a 20 kg child who drinks an average amount of apple juice.
NOTE: Daily cancer risk = Intake x Concentration x Potency / Body Weight
Calculate the maximum daily cancer risks for peanut butter and apple juice based on the 95th percentiles.
Discuss your results briefly.
Variable
Units
Average
5th %ile
95th %ile
Distribution
Peanut butter intake
g/day
11.38
2.00
31.86
Lognormal
Apple juice intake
g/day
136.84
16.02
430.02
Lognormal
Aflatoxin concentration
ug/kg
2.82
1.00
6.5
Lognormal
UDMH concentration
ug/kg
13.75
0.5
42.00
Lognormal
Aflatoxin potency
kg-day/mg
17.5
4.02
28.33
Normal
UDMH potency
kg-day/mg
0.49
0.00
0.85
Normal
Explanation / Answer
answer:
a) Calculate the daily cancer risk for a child who weighs 20 kg and who eats an average amount of peanut butter.
sol: Daily Cancer risk - Pea nut Butter intake = 28.08015 kg-day/ mg
Daily Cancer risk - Apple juice intake = 46.097975 kg-day/mg
b) Calculate the maximum daily cancer risk for peanut butter and apple juice based on the 95th percentiles.
Daily cancer risk - Pea nut Butter intake = 293. 342985 kg-day/mg
Daily cancer risk - Apple juice intake = 767.5857 kg-day/mg
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