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6. Huntington disease is caused by a single dominant gene (H) and results in pro

ID: 166581 • Letter: 6

Question

6. Huntington disease is caused by a single dominant gene (H) and results in progressive mental and neurological damage. The disease is usually symptomatic when a person is between 30 and 50 years old and the patient usually dies within 15 years of diagnosis. Approximately 1 in 25,000 Caucasians have this disease. Huntington disease has not been associated with any other disease, now or in the past. Why might natural selection not have eliminated such a deleterious gene from the population? (2 points) 6. Huntington disease is caused by a single dominant gene (H) and results in progressive mental and neurological damage. The disease is usually symptomatic when a person is between 30 and 50 years old and the patient usually dies within 15 years of diagnosis. Approximately 1 in 25,000 Caucasians have this disease. Huntington disease has not been associated with any other disease, now or in the past. Why might natural selection not have eliminated such a deleterious gene from the population? (2 points) 6. Huntington disease is caused by a single dominant gene (H) and results in progressive mental and neurological damage. The disease is usually symptomatic when a person is between 30 and 50 years old and the patient usually dies within 15 years of diagnosis. Approximately 1 in 25,000 Caucasians have this disease. Huntington disease has not been associated with any other disease, now or in the past. Why might natural selection not have eliminated such a deleterious gene from the population? (2 points)

Explanation / Answer

Huntington's disease easy day was treating human genetic disease the people who inherit this genetic disease will have abnormal dominant allele which disrupt the function of nerve cells slowly disturbing the control over their bodies and the mind leading to death. As it is a dominant allele the persons with one parent with this disease have 50% chances of developing the disease. Hunting X belongs to class of genetic diseases that can escape natural selection it is often invisible to natural selection as it does not affect people until after they have reproduced in this way the earliest escape natural selection sneaking into next generation. But today genetic testing can help people in identifying Huntington allele before the onset of the disease and before they have made reproductive choices.

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