Help! In a test population of 1000 people. 200 display albinism. You hypothesize

Question

Help!

In a test population of 1000 people. 200 display albinism. You hypothesize that this trait follows Mendelian genetics with a 3:1 ratio of non-albinism to albinism. Use the X^2 test to determine whether the data support the hypothesis or not. Show your steps and explain your reasoning. X^2 = Sigma [(O - E)^2/E where O is the observed number of individuals in a defined class, and E is the expected number of individuals in a defined class based on the hypothesis. the Sigma symbol indicates that you should sum the results for each defined class.

Explanation / Answer

lets parental genotypes be Aa X Aa

expected(E) number of individuals with non abinism phenotype is= (3/4)(1000)= 750

expected(E) number of inividuals with albinism is= (1/4)(1000)= 250

degree of freedom(d.o.f)= no. of phenotype studied-1=3-1=2(AA,Aa,aa)

probability for p- Value is always closest to the chi square calculated value, at d.o.f=2, p=0.001(significant)

thus, the test is significant. also, our calculated value is=13.33 and table value is=13.82 thus the null hypothesis is accepted.

phenotype ratio= 3:1 PARENTAL A a A AA(non-albinism) Aa(non albinism) a Aa(non-albinism) aa(albinism)

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