Identify The Following Chromosome Rearrangements Imagine there are eight genes o

Question

Identify The Following Chromosome Rearrangements

Imagine there are eight genes on chromosome 1, with their relative positions on the chromosome indicated as follows, with the “-“ depicting the position of the centromere: ABC-DEFGH

Imagine also there are eight genes on chromosome 2, with their relative positions on the chromosome indicated as follows, with the “-“ depicting the position of the centromere: 123-45678

1. Please name the kind of rearrangement that will produce the following arrangement of genes on chromosome 1: AFED-CBGH

2. Please name the kind of rearrangement that will produce the following arrangement of genes on the two chromosomes:    A567BC-DEFGH AND   123-48

3. Please name the kind of rearrangement that will produce the following arrangement of genes on the two chromosomes:   ABC-D678      AND    123-4FGH

Explanation / Answer

Answer: 1). Pericentric inversion An inversion is a chromosome rearrangement in which a segment of a chromosome is reversed end to end. An inversion occurs when a single chromosome undergoes breakage and rearrangement within itself. Inversions are of two types: paracentric and pericentric. Paracentric inversions do not include the centromere and both breaks occur in one arm of the chromosome. Pericentric inversions include the centromere and there is a break point in each arm.

2). Nonreciprocal translocation

Nonreciprocal translocation involves the transfer of genes from one chromosome to another nonhomologous chromosome.

3). Reciprocal translocations

Reciprocal translocations involves an exchange of genetic material between nonhomologous chromosomes

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