The shibire gene in fruit flies is the Drosophila version of the dynamin gene. A

Question

The shibire gene in fruit flies is the Drosophila version of the dynamin gene. A
temperature sensitive mutation was discovered in this gene in flies, and the most obvious phenotype that was observed upon bringing flies up to the restrictive temperature (temperature in which the mutant shibire protein cannot function) was complete paralysis. This was because the nonfunctional shibire protein in these mutants caused a complete disruption of all synaptic transmission in neurons which, you know, requires the balanced cycling of synaptic vesicles through exo and endocytosis.   

a. Normally, a stain that would specifically label the membrane of synaptic vesicles would heavily label the entire terminal because many synaptic vesicles are packed into the volume of the cytoplasm in the presynaptic terminal. In these shibire mutant flies at the restrictive temperature, where would this same synaptic vesicle membrane label localize?

Explanation / Answer

Answer= stain would label the the membrane of synaptic vesicles would heavily label the entire terminal & many synaptic vesicles are packed into the volume of cytolpasm in the presynaptic terminal .

then these synaptic vesicles contains neurotransmitter .

fusion of vesicles with presynaptic membrane causes neurotransmitters to be released acrss the synaptic cleft

binds to a receptor proteins on postsynaptic membrane

that means stain label synaptic vesicles localized in the presynaptic membrane

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