LDL is known as \"bad\" cholesterol. Which of the following statements does NOT
ID: 167664 • Letter: L
Question
LDL is known as "bad" cholesterol. Which of the following statements does NOT help to explain why LDL has earned this title?
a
When cholesterol is abundant in a cell, the expression of LDL receptors is decreased.
b
The cholsterol in LDL particles is different from the cholesterol in HDL particles.
c
LDL particles are removed from the blood stream only via receptor-mediated endocytosis.
d
High levels of LDL in the blood stream indicate that there is excess cholesterol in the peripheral tissues.
a
When cholesterol is abundant in a cell, the expression of LDL receptors is decreased.
Explanation / Answer
1. d. High levels of LDL in the blood stream indicate that there is excess cholesterol in the peripheral tissues.
Receptors help bind high levels of LDL in the blood stream and be removed from the body. Hence this LDL would not accumulate in the peripheral tissue and be of no risk to the individual through receptor-mediated endocytosis. Thus LDL in such cases cannot be termed as bad due to the functionality lipoprotein receptors.
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