Glucose is necessary because it is used by almost all tissues for energy and bio

Question

Glucose is necessary because it is used by almost all tissues for energy and biosynthesis, and the brain relies heavily on glucose as an energy source. During their three-week pre-marathon self-experiment, both Dave’s and Michael’s livers had to produce some glucose. Which of the following molecules could be used by the liver to create the glucose that is needed to supply the brain and other tissues in a healthy person on a normal diet? (Select ALL that apply)

Lactate

Even-chain fatty acids

Acetyl-CoA

Pyruvate

Alanine

Leucine

Glycerol

Lactate

Even-chain fatty acids

Acetyl-CoA

Pyruvate

Alanine

Leucine

Glycerol

Explanation / Answer

Gluconeogenesis involves synthesis of glucose from non-carbohydrate precursor sources, this is an important process to maintain blood glucose levels at the time of starvation or heavy exercise. The dependency of glucose on brain and RBC’s is vital to survival.

There are various sources through which glucose is produced using other precursors such as :

Therefore the correct options are: Lactate, Acetyl-CoA, Pyruvate, Alanine, Glycerol

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