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Biochemisty The Na^+-glucose seaport system of intestinal epithelial cells coupl

ID: 171613 • Letter: B

Question

Biochemisty

The Na^+-glucose seaport system of intestinal epithelial cells couples the "downhill" transport of two Na^+ ions into the cell to the "uphill" transport of glucose, pumping glucose into the cell against its concentration gradient. If the Na^+ concentration outside the cell ([Na^+]_out) is 159 mM and that inside the cell ([Na^+]_ln) is 23.0 mM, and the cell potential is -54.0 mV (inside negative), calculate the maximum ratio of [glucose]_in to [glucose]_out that could theoretically be produced if the energy coupling were 100% efficient. Assume the temperature is 37 degree C.

Explanation / Answer

ratio= (sodium concentration outside/sodium concentration inside) *cell potential

=>159/23 *54=>6.91*54=>373.33