How do DNA polymerase I and DNA Polymerase III differ? Multiple Choice A.) DNA P

Question

How do DNA polymerase I and DNA Polymerase III differ?

Multiple Choice

A.) DNA Polymerase III synthesizes the majority of the DNA, while DNA Polymerase I synthesizes DNA in the regions where the RNA primers were laid down on the lagging strand.

B.) DNA Polymerase I synthesizes the majority of the DNA, while DNA Polymerase III synthesizes DNA in the regions where the RNA primers were laid down on the lagging strand.

C.) DNA Polymerase I synthesizes DNA only on the leading strand and DNA Polymerase III synthesizes DNA only on the lagging strand.

D.) DNA Polymerase III is the primary DNA polymerase in eukaryotes, while DNA polymerase I is the primary DNA polymerase in prokaryotes.

E.) DNA Polymerase III synthesizes DNA only on the leading strand and DNA Polymerase I synthesizes DNA only on the lagging strand.

Explanation / Answer

In prokaryotes such as E.coli, DNA polymerase III catalyzes the addition of deoxyribonucleotides to RNA primers, either continuously on the leading strand or discontinuously by the synthesis of Okazaki fragments on the lagging strand. The RNA primers subsequently are removed and replaced with DNA chains which is accomplished by DNA polymerase I.

Therefore answer is (A)

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