Question 1) If glucose-6-phosphatase were deficient in liver, what would best ch

Question

Question 1) If glucose-6-phosphatase were deficient in liver, what would best characterize the expected change in metabolism relative to the normal state?: A. decreased energy supply to the liver and hepatic cell death B. hyperglycemia after a normal meal C. decreased rate of ketogenesis D. depletion of glycogen stores in liver E. hypoglycemia one or two hours after a meal

Question 2) A positive nitrogen balance would be expected in all of the following conditions EXCEPT : A. growing children. B. pregnancy. C. consumption of a diet with increased protein. D. recovery from trauma or surgery.

Question 3) Oxidation of fatty acids in liver mitochondria may facilitate gluconeogenesis by: A. supporting the phosphorylation of ADP. B. forming acetyl CoA which can contribute to the net synthesis of glucose. C. reducing FAD and NADP+. D. transporting carnitine into mitochondria. E. decreasing the dependence of phosphorylation of ADP on oxygen consumption.

Explanation / Answer

1 D- The deficiency of glucose-6-phosphate causes hypoglycemia since the liver can not release glucose in to the blood.

2 C- A positive nitrogen balancce is expected to be found in pregnant women, growing children and recoverry from trauma and surgeries due to the development of new tissues and growth, hence the correct answer is C. consumption of a diet with increased protein.

3 B- In Liver mitochondria the oxidation of fatty acids may lead to gluconeogenesis by forming acetyl CoA which leads to the net synthesis of glucose.

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