When levels of blood calcium decrease, parathyroid hormone is released from the

Question

When levels of blood calcium decrease, parathyroid hormone is released from the four nodular parathyroid glands located on the posterior thyroid. decrease reabsorption Parathyroid hormone causes an increase in the number of osteoclasts and greater rates of bone resorption Increase osteoblasts At the level of the kidney, parathyroid hormone will decrease the amount of calcium excreted by increasing reabsorption from the kidney tubules calcitriol to calcitriol Parathyroid hormone increases the renal conversion of calcitriol to calcitriol, which secondarily works to increase calcium levels in the blood osteogenic: stem cells osteocytes inhibition of by parathyroid hormone occurs as a result of a decreased production of organic matrix

Explanation / Answer

Inhibition of osteoblasts by parathyroid hormone occurs as a result of a decreased production of organic matrix.

Osteobalsts are the cells produced from stem cells after differentiation in the bone. These cells help in building the bone matrix.

Osteobalsts differentiate to form osteoclasts. Osteobalsts help in building the bone matrix where as osteoclasts help in the break down of the bone matrix by producing collagenase enzyme.

So when there is low organic matrix , the osteoblasts will be inhibited by parathyroid hormone resulting in decreased osteoclasts secretion.

As a result of direct actions on the target cells of the bone and kidneys along with an indirect action on the small intestine, Parathyroid hormone works to increase the blood calcium levels.

Parathyroid hormone is initiated when there is a decreased level of blood calcium, so the above mentioned processes occur.

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