The disease Adrenoleukodystrophy (ALD) occurs when there is an accumulation of l

Question

The disease Adrenoleukodystrophy (ALD) occurs when there is an accumulation of long fatty acid chains in the body. ALD results in neurodegeneration and problems with vision, hearing, and motor coordination. In Drosophila, the bubblegum gene is similar to the human gene that when mutant causes ALD. Mutations in bubblegum result in fly vision defects. Mutations in the curly gene result in curly wings You want to study the linkage between bubblegum and curly so you do this cross Curly wings, vision Wild-type female defects male bgm bgm cut cu bgm bgm Cu cu 99 Vision defects, 395 Wild-type normal wings 405 curly wings, 101 curly wings, normal vision vision defects Which classes of progeny are the parental types? A. O type & Vision defects, normal wings B. O type & Curly wings, vision defects c. O Vision defects, normal wings & Curly wings, normal vision D. Curly wings, vision defects & Curly wings, normal vision

Explanation / Answer

Answer:

1). B. wild-types & curly wing, vision defects.

Generally parental combinations are more than the recombinants. So the parental combinations are wild-types and curly wing, vision defects.

2). B. Map #2

Vestigial is mention in the two pairs, so that vestial gene is the middle gene. Hence, the second map is correct.

3). C. 20.0 cM

Curly---13---vestigial---7---bubble gum

Curly -------------20--------------bubble gum

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