1. In trimeric G proteins, GTP binds to: the alpha subunit. the beta subunit. th
ID: 173622 • Letter: 1
Question
1. In trimeric G proteins, GTP binds to:
the alpha subunit.
the beta subunit.
the gamma subunit.
the activated trimer.
2. Phosphatidylinositol 4,5-bisphosphate (PIP2) is cleaved by phospholipase C into:
1,2-diacylglycerol (DAG).
phosphatidylinositol (PI).
inositol 1,4,5-trisphosphate (IP3).
1,2-diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3)
3. 1,2-diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) are cleaved from phosphatidylinositol 4,5-bisphosphate (PIP2) by the enzyme:
adenylyl cyclase.
phosphodiesterase.
phospholipase C.
protein kinase C.
a.the alpha subunit.
b.the beta subunit.
c.the gamma subunit.
d.the activated trimer.
Explanation / Answer
In General protein coupled receptor the GTP binds to alpha subunit of the trimeric G protein. By the action of phospho lipase C , the given compound cleaved to diacylglecerol and inositol triphosphate. The enzyme is phospholipase C.
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