Suppose that whole exome sequencing is performed on 250 children with IQ greater

Question

Suppose that whole exome sequencing is performed on 250 children with IQ greater than 140, and three novel non-sense mutations are observed in the gene CNS4B, but none are observed in this gene in 4,000 control exome sequences. Does this result establish that CNS4B is involved in high intelligence? Would your answer change if you knew that 0.1% of children with intellectual disability have three copies of CNS4B due to copy number variation? What other type of data from the experiment might you be interested in studying in order to associate genes with intellectual ability?

Explanation / Answer

No this result not establish that CNS4B gene involved in high intelligence.

No ans.will be the same .

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