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Which of the following statements is NOT true about eukaryotic mRNA processing?

ID: 175094 • Letter: W

Question

Which of the following statements is NOT true about eukaryotic mRNA processing?

A 7-methyl-guanosine cap is attached to the 5' end of the mRNA.

It allows for alternative splicing to generate multiple mature mRNAs from one primary transcript.

Most mRNAs require a splicesome to remove introns.

5' capping and 3' poly A tails protect the mRNA from degradation.

All of the statements are true.

A.

A 7-methyl-guanosine cap is attached to the 5' end of the mRNA.

B.

It allows for alternative splicing to generate multiple mature mRNAs from one primary transcript.

C.

Most mRNAs require a splicesome to remove introns.

D.

5' capping and 3' poly A tails protect the mRNA from degradation.

E.

All of the statements are true.

Explanation / Answer

1. Methyl transferase add methyl group in the 7 position to produce 7methyl-guanosine cap to the 5' end of the mRNA.

2. Poly(A) polymerase adds adenine ribonucleotides upto 200 bases at the 3' end of RNA produces poly(A) tail.

3. These two process enhances stability and protect mRNA from degradation by nucleases.

4. Most mRNA requires splicesomes to ensure proper splicing to remove introns.

5. From the above statements says that all the statements are tru. So option 'E' is the correct anser.

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