Below are two oxygen dissociation curves. The one on the left illustrates oxygen

Question

Below are two oxygen dissociation curves. The one on the left illustrates oxygen dissociation curve for hemoglobin that exhibits cooperativity. The one on the right shows what the oxygen dissociation curve for an imaginary hemoglobin that DOES NOT bind O2 in a cooperative manner (in other words, the subunits do not influence each other binding). Complete the series of questions below using the information in these two graphs.

Question 10.5 pts

The percent O2 saturation in the lungs under noncooperative binding is                           [ Select ]                       ["50", "100", "20", "80"]         , and the percent O2 saturation in the lungs under cooperative binding is                            [ Select ]                       ["80", "100", "50", "20"]         .

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Question 20.5 pts

The percent O2 saturation in tissues at rest under noncooperative binding is                           [ Select ]                       ["10", "30", "50", "70"]         , and the percent O2 saturation in tissues at rest under cooperative binding is                            [ Select ]                       ["50", "70", "20", "10"]         .

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Question 30.5 pts

The percentage of O2 DELIVERED to tissues at rest under noncooperative binding is                           [ Select ]                       ["10", "30", "50", "70"]         , and the percentage of O2 DELIVERED to tissues at rest under cooperative binding is                            [ Select ]                       ["10", "70", "50", "30"]         .

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Question 40.5 pts

The percentage of O2 is DELIVERED to exercising tissues under under non-cooperative binding is                            [ Select ]                       ["10", "70", "50", "80"]         , and the percentage of O2 is DELIVERED to exercising tissues under cooperative binding is                            [ Select ]                       ["70", "50", "10", "80"]         .

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Question 50.5 pts

Based on what you have learned from the comparison above, what is the major distinction between the noncooperative binding and the cooperative binding? How does this relate to/impact gas exchange?

The x-axis shows the partial pressure of oxygen (PO2). This is a measure of the amount of oxygen present in a tissue. The blue arrows on thexaxis show the partial pressure of oxygen in various tissues of the body. The y axis shows the oxygen saturation of hemoglobin (o2 saturation). This is the percentage of oxygen-binding sites on hemoglobin molecules that are actually bound to oxygen. Noncooperative binding Cooperative binding 100 100 80 80 60 60 o 40 o 40 20 20 10 20 30 40 50 (60 70 80 90 100 10 20 30 40 50 60 70 80 90 100 tissue during tissue lungs tissue during tissue lungs at rest at rest exercise exercise PO2 (mm Hg) PO2 (mm Hg)

Explanation / Answer

From the above curve the answer to the following questions are as follows:

1. The percent O2 saturation in the lungs under non cooperative binding is 100.

2. The percent O2 saturation in the lungs under cooperative binding is 100.

3. The percent O2 saturation at tissues at rest under non cooperative binding is 70.

4. The percent O2 saturation at tissues at rest under cooperative binding is 50.

5. The percent of O2 delivered to tissues at rest under non cooperative binding is 70.

6. The percent of O2 delivered to tissues at rest under cooperative binding is 50.

7.The percentage of O2 is delivered to exercising tissues under under non-cooperative binding is 50.

8.The percentage of O2 is delivered under cooperative binding is 10.

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