Transamination reactions have equilibrium constants close to unity. What does th

Question

Transamination reactions have equilibrium constants close to unity. What does this mean?

1) In the absence of any other forces, the ratio of products to starting materials is nearly one.
2) Intracellular conditions can dictate the direction the equilibrium favors.
3) The forward reaction is not favored in cells.
4) Aminotransferases can alter the position of the equilibrium.

A. Statements 1, 2, and 3 are accurate. B. Statements 1 and 2 are accurate. C. Statements 1, 2, and 4 are accurate. D. All of the listed statements are accurate.

Explanation / Answer

Transamination reaction is a catalyzed reaction that has equilibrium constant that is close to unity, which means they catalyse the conversion of L and D enantiomers with equal efficiency. Depending on intracellular conditions this reaction is driven in one direction. Aminotransferases do not alter the position of equilibrium, but they favour the direction of the reaction based on the concentration of reactant.

Hence, the correct option is (B) Statements 1 and 2 are accurate.

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