1- After ingesting a bacteria, macrophages process bacterial parts and ‘present’
ID: 176168 • Letter: 1
Question
1- After ingesting a bacteria, macrophages process bacterial parts and ‘present’ them to acquired immunity cells so the acquired immune cells recognize these invaders again in the future. The antigen-presenting proteins ultimately end up in the plasma membrane. Where did it receive the post-translation modification that determined its final location?
The ribosome
The ER
The Golgi body
The vesicle
2- The antigen-presenting proteins arrive at the plasma membrane. Which of the following is required to "deliver" the protein from the vesicle to the plasma membrane? (Choose all correct answers).
a- A V-SNARE
b- Clathrin
c- A G-protein
d- Rab GTPase
a-The ribosome
b-The ER
c-The Golgi body
d-The vesicle
Explanation / Answer
1.
The ER are receive the post-translation modification that determined its final location for synthesized polypeptides in the membrane and lumen of the ER undergo five main modifications before they reach their final destinations:
2. Clathrin is required to "deliver" the protein from the vesicle to the plasma membrane. The clathrin-coated vesicles are composed of two kinds of protein complexes, clathrin and adaptor proteins, which accumulate on the cytosolic side of membranes. Clathrin shows a structural character by assembling into a basketlike frame structure that twists the membrane and determinations vesicle budding. The binding of clathrin to the membranes is mediated by a second class of proteins are called adaptor proteins. Different adaptor proteins are accountable for the collecting of clathrin-coated vesicles at the plasma membrane.
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