Questions 3 and 4: Imagine that you can engineer an mRNA encoding a protein with

Question

Questions 3 and 4: Imagine that you can engineer an mRNA encoding a protein with two conflicting address tags, each of which specifies a different compartment in the cell. You express your engineered mRNA in the cell and look to see where the translated protein product ends up in the cell.

3. Suppose your mRNA encodes a nuclear localization signal AND a signal sequence/peptide. The protein product would be found in which of the following?

Question 3 options:

A) Nucleus

B) Rough endoplasmic reticulum

C) Both

D) Neither

Question 4

Suppose your mRNA encodes a mitochondrial presequence AND a Golgi retention sequence. Where would the protein end up in the cell?

Question 4 options:

A) Mitochondrion

B) RER

C) Golgi

D) All 3 places

Explanation / Answer

3.  Proteins which are transported by the endoplasmic reticulum throughout the cell are marked with an address tag called a signal sequence.

B) Rough endoplasmic reticulum

4. C) Golgi

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