When considering synonymous and nonsynonymous mutations within a population, whi

Question

When considering synonymous and nonsynonymous mutations within a population, which of the following is TRUE?

Nonsynonymous mutations will often be removed by purifying selection

Synonymous mutations will often be removed by purifying selection

The two types of mutations are not distinguished by purifying selection

Only nonsynonymous mutations are known to occur

Only synonymous mutations are known to occur

Nonsynonymous mutations will often be removed by purifying selection

Synonymous mutations will often be removed by purifying selection

The two types of mutations are not distinguished by purifying selection

Only nonsynonymous mutations are known to occur

Only synonymous mutations are known to occur

Explanation / Answer

Synonymous mutations are the mutations in which the DNA nucleotide is miscopied and this cause change in one base pair of RNA copied from DNA. These are point mutations and the change in third codon results in the same amino acid as that of the original codon and therefore there is no change in amino acid.

Non synonymous mutations are the mutations in which the insertion or deletion of the single nucleotide in sequence occurs during transcription of mRNA from DNA. This causes the shift mutation and changes the amino acid which is coded and the protein which is expressed. This type of mutation affect an individual more when compared to the synonymous mutation.

Synonymous mutations which are point mutations can be removed by purifying selection within a population where as nonsynonymous mutations cannot be removed by purifying selection.

Hence, the statement which is true is Synonymous mutations will often be removed by purifying selection.

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