The following are a series of statements about gluconeogenesis and glycolysis. I

Question

The following are a series of statements about gluconeogenesis and glycolysis. Indicate whether each state is true or false. If the statement is false, change the wording so that it is correct .

_____ a.         During gluconeogenesis, phosphoenolpyruvate is formed from pyruvate     and ATP.

_____ b.         Both glycolysis and gluconeogenesis occur primarily in the cytoplasm.

_____ c.          Unlike glycolysis, gluconeogenesis requires GTP and NADPH.

_____ d.         Fructose-2,6-bisphosphate is an activator of gluconeogenesis and an           inhibitor of glycolysis.

_____ e.          In animals but not plants, acetyl-CoA can serve as a precursor for gluconeogenesis.

_____ f.           The enzyme aldolase participates in both gluconeogenesis and glycolysis.

_____ g.          In animals, gluconeogenesis occurs primarily in the heart.

_____ h.          Excess pentoses formed from the pentose phosphate pathway can enter the           gluconeogenic pathway at fructose-6-phosphate.

Explanation / Answer

d

a) FALSE: the decarboxylation of oxaloacetate and hydrolysis of GTP leads to the formation of phosphoenolpyruvate.

b) TRUE: glycolysis occur in cytosol whereas gluconeogensis primarily start in mitochondria.

c) TRUE

d) TRUE

e) FALSE: Acetyl co A cannot be used effectively by animals.

f) FALSE: Aldolase play importatnt role in glycosis and in the reverse pathway of gluconeogenesis.

g) FALSE: gluconeogenesis occure primarily in liver.

h) FALSE: excess pentose is recycled.

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