The Vmax values for certain enzymes can be used as an indication of the relative

Question

The Vmax values for certain enzymes can be used as an indication of the relative importance of various ATP-producing pathways. The Vmax values (in mol substrate/min/g tissue) for several enzymes from the pectoral muscles (chest muscles used for flying) of pigeon and pheasant are listed below

(a) Discuss the relative importance of the various ATP-producing pathways in the pectoral muscles of these birds. (b) Predict oxygen consumption in the two muscles. (c) Judging solely from the data in the table, predict which bird is a long-distance flyer and justify your answer. (d) Why were these enzymes selected for comparison? Would the activities of triose phosphate isomerase and malate dehydrogenase be equally good basis for comparison? Explain.

Enzyme Pigeon Pheasant Hexokinase 3.0 2.3 Glycogen phophrylase 18.0 120.0 PFK-1 24.0 143.0 Citrate synthase 100.0 15.0 Tricylglycerol synthase 0.07 0.01

Explanation / Answer

(a)

(b)

(c)

(d)

-No, the activities of triose phosphate isomerase and malate dehydrogenase are not good for comparison because they catalyze reactions near equilibrium and are not at regulatory control points.

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