What would be the consequence of ectopically expressing Hoxd11 throughout the de

Question

What would be the consequence of ectopically expressing Hoxd11 throughout the developing mouse limb bud? Note--like humans, each mouse hand/foot has 5 digits.

convert the thumb (first digit) into a middle digit

convert the index digit (second digit) into a middle digit

convert the thumb into an index digit

both a and b

both b and c

a.

convert the thumb (first digit) into a middle digit

b.

convert the index digit (second digit) into a middle digit

c.

convert the thumb into an index digit

d.

both a and b

e.

both b and c

(c) Mor gene clusters DigSer Lo abdA Abde Hosat Hoaal Hara3 Harad HoaaS Nosed Mesa? Masad Hosato Hara Moxa13 Houbt Novb2 Mar03 HoxD4 HotS Nowit6 Heeb7 Hoabe Hote Hard Hares Noet0 Nore11 Mase12 Mere13 Manda Horde only Hanna fa tt, t2+ 13 Nants, 10, 11+12 Posterior

Explanation / Answer

Ans-B. Convert the index digit (second digit) into a middle digit.

HoxD11 expression at the embryonic index finger area will bring a combination of HoxD9+10+11, which will develop a middle finger. None of the options will result by the expression of HoxD11 at the thumb area, making a combination of HoxD9+11.

Related Questions

Navigate

• Browse (All)
• Browse W
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.