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In a giant mutant background, hunchback and Krüppel are bound to their sites in

ID: 177372 • Letter: I

Question

In a giant mutant background, hunchback and Krüppel are bound to their sites in parasegments 2 and 3 but giant is not, resulting in eve expression in both parasegments 2 and 3.

In a giant mutant background, hunchback and bicoid are bound to their sites in parasegments 1, 2, and 3 but giant is not bound to its sites, resulting in eve expression in parasegments 1, 2, and 3.

In a giant mutant background, hunchback and bicoid are bound to their sites in parasegment 3 but giant is not, resulting in eve expression in both parasegments 2
and 3.

In a giant mutant background, hunchback and Krüppel are bound to their sites in
parasegment 2 but giant is not, resulting in eve expression in both parasegments 2
and 3.

In a giant mutant background, hunchback and bicoid are bound to their sites in parasegments 2 and 3 but Krüppel replaces Giant in Giant binding sites, resulting in no change in eve expression.

a.

In a giant mutant background, hunchback and Krüppel are bound to their sites in parasegments 2 and 3 but giant is not, resulting in eve expression in both parasegments 2 and 3.

b.

In a giant mutant background, hunchback and bicoid are bound to their sites in parasegments 1, 2, and 3 but giant is not bound to its sites, resulting in eve expression in parasegments 1, 2, and 3.

c.

In a giant mutant background, hunchback and bicoid are bound to their sites in parasegment 3 but giant is not, resulting in eve expression in both parasegments 2
and 3.

d.

In a giant mutant background, hunchback and Krüppel are bound to their sites in
parasegment 2 but giant is not, resulting in eve expression in both parasegments 2
and 3.

e.

In a giant mutant background, hunchback and bicoid are bound to their sites in parasegments 2 and 3 but Krüppel replaces Giant in Giant binding sites, resulting in no change in eve expression.

Adjacent genes EVENSOPPED (EVE) ADAM APPLE mRNA -7,4 -55 -3,9 -1.1 +1.5 +3.2+4.8 +6.6 +8,4 kb eve enhancer modules (stripe number) a A2 Giant Kruppel eve repressors Stripe 2 enhancer module ever activators Bicoid Hunchback (b) Distribution ofgap gene expression Anterior Posterior Position of 2nd stripe hundback relative to gap gene expression Kruppel Gap expression E Parasegment 1 2 3 4 5 6

Explanation / Answer

The option 4 is true, in case of giant mutant, there will no change of expression of eve gene. This is because the Kruppel gene regulates the expression of even skipped, not by Giant.

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