1. When Na+-channel is opened in a receptor, it will lead to a. depolarization b
ID: 177591 • Letter: 1
Question
1. When Na+-channel is opened in a receptor, it will lead to
a. depolarization
b. hyperpolarization
c. repolarization
d. polarization
e. neurotransmitter release
2. When Cl–-channel is opened in the post-synaptic receptor, the
synapse would be
a. an excitatory synapse.
b. an inhibitory synapse.
c. a neutral synapse.
d. an electrical synapse.
e. non-functional synapse.
3. Which receptor is known to be involved in synaptic plasticity that
induces long-term potentiation (LTP)?
a. NMDA glutamate receptor
b. non-NMDA glutamate receptor
c. GABAA receptor
d. mu-opioid receptor
e. nicotinic-ACh receptor
4. Which receptor does barbiturate or diazepam (Valium™) bind to?
a. serotonin receptor
b. norepinephrine receptor
c. opioid receptor
d. NMDA receptor
e. GABAA receptor
5. Which part of the brain does opioid receptors are found where it
regulates the emotional influence of pain perception?
a. basal ganglia
b. cerebellum
c. cortex
d. medial thalamus
e. septal nucleus
6. Which neurotransmitter binds to the CB-receptor (cannabinoid
receptor)?
a. opioid
b. nitric oxide
c. serotonin
d. anandamide
e. acetylcholine
7. Which neurotransmitter (or neuromodulator) is released that
stimulates the parasympathetic system in the erectile response
(which Viagra™ potentiates)?
a. acetylcholine
b. substance P
c. nitric oxide
d. cannabinoid
e. norepinephrine
8. Which receptor is targeted to enhance the inhibition in the
amygdala to produce the anti-anxiety effect in the design of antianxiety
drug treatment?
a. glutamate receptor
b. GABA receptor
c. cananbinoid receptor
d. opioid receptor
e. dopamine receptor
9. Which receptor is targeted to enhance the prefrontal cortex (PFC)
executive function to treat ADHD/ADD?
a. dopamine D4 receptor
b. serotonin receptor
c. NMDA glutamate receptor
d. GABAB receptor
e. nicotinic ACh receptor
10. What is the signal that triggers the vesicular release of
neurotransmitter when action potential arrives at the axon
terminal?
a. Increase in the cytoplasmic concentration of neurotransmitters.
b. Binding of amphetamine to the VMAT.
c. Binding of amphetamine to the transporter.
d. Na+ ion entry into the axon terminal.
e. Ca++ ion entry into the axon terminal.
11. Which experiment is used to prove that release of dopamine
induced by amphetamine is not coming from vesicular release?
a. dopamine is released by activation of action potentials in the
presynaptic neuron without amphetamine.
b. dopamine release only in the presence of magnesium.
c. dopamine release is dependent on depolarization of post-synaptic cell.
d. dopamine release from axon terminal can occur in Ca++ free medium.
e. dopamine release is quantal in amount.
12. Which drug can stimulate the sympathomimetic effects?
a. MDMA
b. Valium™
c. Prozac™
d. amphetamine
e. nicotine
Explanation / Answer
Ans. A
The opening of channels that let positive ions flow into the cell can cause depolarization. Example: Opening of channels that let Na+ into the cell
2 Ans an inhibitory synapse.
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