The following measures are important for preventing future antibiotic resistance

Question

The following measures are important for preventing future antibiotic resistance:

Select one:

a. Developing new therapies that are extended (longer) treatment courses.

b. Developing new treatments that target multiple pathways in the pathogen.

c. Developing more broad spectrum antibiotics.

d. Developing new antibiotics that are analogs (modifications) of currently used compounds.

e. All of the choices.

The following is TRUE about complement Factor I EXCEPT for:

Select one:

a. Interacts with C3b.

b. Interacts with C4b.

c. Blocks the formation of MAC.

d. Is a serine protease.

e. Uses additional cofactors for regulation.

Which of the following is the easiest way for bacteria to develop antibiotic resistance?

Select one:

a. Mutate a gene that regulates the antibiotic resistance genes.

b. None of the choices.

c. Generate a mutation to alter the target protein.

d. Acquire drug resistance genes via lateral gene transfer.

e. Add a functional group to the antibiotic.

The global appearance the “super bugs”:

Select one:

a.
Is overrated and presented as propaganda

b. Is easy to manage with current treatments

c. Was completely unpredictable

d. All of the answers

e. None of the answers

Explanation / Answer

1. b. Developing new treatments that target multiple pathways in the pathogen.

Bacteria attain drug resistance when they are exposed to single type of antibiotic for extended periods of time. THe bacteria transform my taking up drug resistant plasmids and develop mechanisms to denature the drug. If a drug is developed which can target multiple pathways at a time, the chances of attaining resistance becomes very low.

2. c. Blocks the formation of MAC.

Factor I actually helps in the formation of Membrane Activation Complex MAC.

3. d. Acquire drug resistance genes via lateral gene transfer.

Bacteria attain drug resistance coding plasmids from the neighbouring bacteria or parents.This happens very frequently.

4. c. Was completely unpredictable

Superbugs are bacteria which are resistant to the most advanced antibiotics available. It is very difficult to treat those infections.

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