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You are a detective trying to figure out the mutation that occurred to the X-men

ID: 177899 • Letter: Y

Question

You are a detective trying to figure out the mutation that occurred to the X-men: Wolverine, Storm and Professor X. Given the Nomal DNA sequence below, identify the nucleotide that mutated for each mutant, the resulting RNA nucleotide, the protein product and the type of mutation of each mutant. Normal DNA sequence: 5' -ATG CTT ACT GCA CCA GTG TGC AAA AGG GCG ... 3' Mutant I: Wolverine 5' -ATG CTT ACT GCG CCA GTG TGC AAA AGG GCG ...3' Mutant II: Storm 5' -ATG CTT ACT GCA CCA GTG TGA AAA AGG GCG ...3' Mutant III: Professor X 5' -ATG CTT GCT GCA CCA GTG TGC AAA AGG GCG ... 3'

Explanation / Answer

NORMAL DNA   5’ ATG CTT ACT GCA CCA GTG TGC AAA AGG GCG 3’

MUTANT 1            5’ ATG CTT ACT GCG CCA GTC TGC AAA AGG GCG 3’

MUT 1 mRNA     5’AUG CUU ACU GCG CCA GUC UGC AAA AGG GCG

PROTEIN              M L T A P V C K R A

MUTANT 2          5’ ATG CTT ACT GCA CCA GTG TCA AAA AGG GCG

MUT2 mRNA      5’ AUG CUU ACU GCA CCA GUG UCA AAA AGG GCG

PROTEIN 2           M L T A P V S K R A

MUTANT 3          5’ ATG CTT GCT GCA CCA GTG TGC AAA AGG GCG 3’

MUT3 mRNA      5’ AUG CUU GCU GCA CCA GUG UGC AAA AGG GCG 3’

Protein 3              M L A A P V C K R A