http://tinypic.com/view.php?pic=53mqfd&s=9 Bonus: The study of biochemical mutan

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Bonus: The study of biochemical mutants in organisms such as Neurospora has demonstrated that some pathways are branched. The data shown above illustrate the branched nature of the pathway resulting in the synthesis of thiamine.

Which mutation(s) from the data table indicate that this is not a linear pathway?

a. the results of the thi-1 mutation test only b. the results of the thi-2 mutation test only c. the results of the thi-3 mutation test only d. the results of the thi-1 and thi-2 mutation tests when considered together e. the results of the thi-2 and thi-3 mutation tests when considered together f. the results of the thi-1 and thi-3 mutation tests when considered together

Explanation / Answer

By looking at (d) the results of the thi-1 and thi-2 mutation tests when considered together

One can determine the branched nature of the pathway resulting in the synthesis of thiamine as pyrimidine and thiazole are important for the thiamine process. Inspite of their presence,thiamine mutants generation indicates the role of multiple genes in the process which affects the transcription and translation.

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