Humans have ~ how many traits? What is the inheritable genetic burden? How many
ID: 178803 • Letter: H
Question
Humans have ~ how many traits? What is the inheritable genetic burden?
How many protein genes?
How man rRNA and tRNA genes
How many other ncRNA genes
What percentage of DNA codes for proteins versus regulatory regions.
What percentage is jumping gene?
Use diagrams to illustrate the modular nature of genes and proteins.
How many RNA species are encoded by the genome? What is RNA PET? What is an EST?
How are DHS sites mapped and how many have been detected? How are protein binding sites on promoters or upstream regulatory regions mapped?
Illustrate the mechanisms of epigenetic imprinting.
Explain the methylation of histones and its function
What are chromo, bromo, PHD and SET domains?
What alkylation sites or methylation sites exist in the genome.
What are histone acetyl transferases?
Explain how CpG islands are methylated?
Explain the function of the DNMT3A/B and DNMT1 in de novo methylation and the propagation of existing methylation.
Explanation / Answer
Humans have ~ how many traits? What is the inheritable genetic burden?
Altogether we have 25, 0000 traits. The genes residing on our chromosomes are responsible for different traits in our body. Genetic burden is the number of diseases or genetic conditions a person can get as a result of inherited traits. As we know humans, due to the effect of inheritance they will carry intrinsic disease burden and the inheritance might be through mutations, genetic and chromosomal (recessive, autosomal, dominant, X or Y linked gene mutations)
How many protein genes?
In our body, 20,848 (J.Craig Venter and Colleagues at Celera Genomics-2013 report) genes have been identified which can code for proteins.
How man rRNA and tRNA genes
In human cell we can find more than 200rRNA genes/haploid genome and 497 tRNA genes.
How many other ncRNA genes
The RNA which will not produce any protein are known as Non-coding RNA genes. Examples are tRNAs, rRNAs, snoRNAs, snRNAs, microRNAs, siRNAs, scaRNAs, exRNAs, piRNAs, Xist and HOTAIR
What percentage of DNA codes for proteins versus regulatory regions.
1/25*100=4%. 1% only will code for proteins and 25% will code for regulatory elements.
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