What is the name of the enzyme that inactivates cyclic adenosine monophosphate?

Question

What is the name of the enzyme that inactivates cyclic adenosine monophosphate? Based on the table show the units of measurement for cyclic AMP? After removal of old medium, the cells were washed two times with Hanks' balanced salts solution and incubated in 3 ml of Ham's F-10 at 37degree. Norepinephrine (NE) was present at 0.1 mM and cycloheximide (CH) at 25 mu g/ml. At the end of the first 4-hr incubation, the medium was removed, the cells were washed once, and 3 ml of medium containing the indicated drug were added for a second 10-min incubation. Cyclic AMP and phosphodiesterase were determined as described under Materials and Methods. The results represent the mean plusminus SEM (n = 4 for phosphodiesterase; n = 3 for cyclic AMP). The experiment was repeated three times.

Explanation / Answer

Phosphodiesterase inhibits cAMP by dephosphorylation of cAMP to AMP. Based on the table, units for measurement of cAMP is pmoles/mg of protein.

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