November 24, 2015 hat is the trigger for acetylchol (ACh) release into the synap

Question

November 24, 2015 hat is the trigger for acetylchol (ACh) release into the synaptic cleft of a neuromuscular junction? Check all that apply 14 o stimulation of the presynaptic membrane releases ACh ia second messenger system o an action potential arrives at the axon terminal acetylcholinesterase opens vesicles, allowing ACh to diffuse into the synaptic cleft contraction of nearby muscle cells stimulates the release of ACh from surrounding neurons of the same motor unit o voltage-gated Ca channels are opened o contraction of nearby muscle cells stimulates the release of ACh from surrounding neurons via gap junctions Describe the structure of the neuromuscular junction. Compare the anatomy and parasympathetic divisions urotransmitters and receptors the somatic motor, sympathetic 15. Complete the sentences using the word bank. acetylcholine (2x) adrenergic autonomic nicotinic muscarinic norepinephrine parasympathetic somatic L sympathetic The efferent division of the peripheral nervous system is further divided into the (1) division, which is mostly under involuntary control, and the (2) division, which is mostly under voluntary control. There are two divisions of the autonomic nervous system. (3) neurons cause physiological changes generally associated with increased physical activity such as exercising which will bind to These neurons secrete the neurotransmitter (4) receptors on the target tissue. There are several receptor types in (5) this division, including alpha and beta. The other division of the autonomic nervous system is the whose neurons control the physiological state generally associated with resting. These neurons secrete the neurotransmitter (7) which will receptors on their target tissue. bind to (8) The neurons of the somatic division of the peripheral nervous system release which binds to (10) neurotransmitter (9) receptors on their target tissue Compare and contrast the anatomy and chemical communication of the sympathetic and parasympathetic branches. Compare the anatomy neurotransmitters and receptors of the somatic motor, sympathetic, and

Explanation / Answer

14. Trigger of acetylcholine release into synaptic cleft of neuromuscular junction.

Answer : Step 1: An action potential arrives at the axon terminal

Step 2: Voltage gated Ca2+ channels are opened

Step 3: Stimulation of presynaptic membrane releases Ach via second messenger system (Calcium)

When Calcium channels open, calcium rush into the cytosol which triggers the release of acetylcholine from presynaptic membrane (nerve cell) to synaptic cleft (Space between muscle and nerve cell). Acetylcholine binds to postsynaptic membrane (muscle cell) triggering Na+ channels which causes the muscle contraction.

15. answer 1. Autonomic 2.Somatic 3. Sympathetic 4.Norepinephrine 5. adrenergic 6. parasympathetic 7. acetylcholine 8. muscarinic 9. acetylcholine 10.nicotinic

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