Which is a candidate gene that is linked to ADHD? a. D2 receptor deficit in chro

Question

Which is a candidate gene that is linked to ADHD?

a. D2 receptor deficit in chromosome 11 in q22-23 region that encodes for D2 receptor.

b. ADHD is a sex-linked disorder associated with sex chromosome

c. ADHD is not a genetic disorder, no genes are associated with it.

d. 2-repeat in the DRD4-2R gene allele that encodes D4 receptor

e. 7-repeat in the DRD4-7R gene allele that encodes D4 receptor

What did longitudinal study of ADHD patients over the course of 10 years showed?

a. Behavioral therapy is more effective than pharmacotherapy.

b. Pharmacotherapy is ineffective.

c. Pharmacotherapy therapy significantly improves the condition while

behavioral is ineffective.

d. Neither behavioral therapy nor pharmacotherapy is effective in treating ADHD patients.

e. ADHD patients are addictive to Ritalin.

Explanation / Answer

1). e. 7-repeat in the DRD4-7R gene allele that encodes D4 receptor

Attention deficit hyperactivity disorder (ADHD) is a genetic, neuro-developmental disease, in which patients suffer from executive functions such as in controlling their attention and inhibitory control. The 7-repeat in the DRD4-7R gene allele that encodes D4 receptor is a candidate gene in the pathogenesis of ADHD. In affected children, their behaviour and hyperactivity does not correlate with their age. The symptoms appear by the age of six to twelve years and symptoms lasts for more than six months.

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