using a single Holliday structure how can you get either an addition transductan
ID: 180373 • Letter: U
Question
using a single Holliday structure how can you get either an addition transductant or a substitution transductant?This is correlation with recombination events that occur during specialized lambda phage transduction. using a single Holliday structure how can you get either an addition transductant or a substitution transductant?
This is correlation with recombination events that occur during specialized lambda phage transduction. using a single Holliday structure how can you get either an addition transductant or a substitution transductant?
This is correlation with recombination events that occur during specialized lambda phage transduction.
Explanation / Answer
Robin holliday was the one who proposed his obsrvation as holliday model.
According to this model,Genetic recombination occurs between two nonsister chromatids to form the Heteroduplex DNA...were the cuts formed in the chromatids will lead to the cross bridge formation between nonsiter chromatids .
Heteroduplex DNA are formed by various stepps leading to the formation of addition transductant other than the existing form,as follow :
This heteroduplex mismatch may carry mutation also, but at many instance this can be corrected by the enzymatic correction...Therfore the resuting molecules may carry either wild type allele/ mutants,depending upon the type of allele excised.
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