Serotonin interacts with at least 15 different receptors in the body. Serotonin

Question

Serotonin interacts with at least 15 different receptors in the body. Serotonin receptors in the human brain begin to decline after age 25. A reduction in the serotonin receptor known as 5-HT2A has been linked to depression in middle aged humans. Data from a study comparing the number of 5-HT2A receptors found inpatients cells over a 10 year period are shown below. Use the data above to calculate the rate of decline in 5-HT2A receptors for the 10 years of this study. Give your answer to the nearest whole number.

Explanation / Answer

sum of all the number of receptors per cell is 1226

decline rate per cell

=(7/220)*1226 = 39

=(6/213)*1226 =35

=(6/207)*1226 = 36

=(6/201)*1226 = 37

=(5/195)*1226 = 31

The entire rate of decline in the period of 10 years is 39-31= 8 receptors/cell

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