The specific way, addiction works, using Cocaine as an example is which of the f

Question

The specific way, addiction works, using Cocaine as an example is which of the following? Choose the most complete answer. Cocaine causes an increase in post synaptic release dopamine in the limbic center, the pleasure center, which means that eventually the receptors will be up regulated requiring more cocaine to produce the same sensation of pleasure. Cocaine causes an increase in dopamine which means that the receptors for cocaine at the postsynaptic site will increase in number. Cocaine causes an increase in dopamine in the limbic system which means that the receptors will be killed by the dopamine leading to the quest for more cocaine. Cocaine causes an increase in post synaptic dopamine release in the cerebral cortex, the pleasure center, what means that eventually the receptors will be down regulated requiring more cocaine to produce the same sensation of pleasure.

Explanation / Answer

Option D

Cocaine blocks the dopamine transport system in the brain hence the amount of dopamine increases at the synaptic gap. This causes the downregulation of dopamine receptors and body produces less dopamine. So now more amount of cocaine is required to produce same amount of pleasure. And now when the cocaine doses are interrupted, the person feels opposite of pleasure that is fatigue, depression and altered moods.

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