64. A neurotransmitter that allows negatively charged chloride ions to enter pos
ID: 181533 • Letter: 6
Question
64. A neurotransmitter that allows negatively charged chloride ions to enter postsynaptic cell causes (IPSP) postsynaptic potentials the of the down the rotransmitter B) inhibitory C) immediate cell because the membrane would become as the inside becomes more negative death as chloride blocks the action of ATP postsynaptic potentials because the membrane would begin to depolarize as the inside becomes more negative E) no change in resting potential, because only sodium and potassium ions are involved in maintaining resting potentialExplanation / Answer
Answer - B
Resting membrane potential = -60mV
When nerve impulse arrives, voltage gated Na+ channels open due to change in membrane potential (from -60mV to -40mV). This causes an inflow of Na+ ions, raising the membrane potential to +30mV. At this voltage, these voltage gated Na+ channels are inactivated, and the voltage gated K+ channels are activated, K+ flows rapidly out of the cell, returning the membrane potential to -60mV.
If the post-synaptic neuron allows negatively charged Cl- ion into the cell, the inside of it becomes more negative (hyperpolarization), and thus, it will require a greater impulse to reach the threshold of an action potential.
For example (not a realistic), if inward flow of Cl- ion causes the membrane potential to fall from -60mV to -80mV, it will require a higher impulse to reach to -40mV than did in normal case (mentioned in first paragraph).
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