Which of the following statements is/are TRUE? (i.e. select ONLY the answer(s) t
ID: 186882 • Letter: W
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Which of the following statements is/are TRUE? (i.e. select ONLY the answer(s) that is/are TRUE.) Post-transcriptional modification of the 3 ends of eukaryotic mRNA occurs prior to splicing and inside the nucleus Post-transcriptional modification of the 3' ends of eukaryotic mRNA is known as polyadenylation. The molecule Poly-A polymerase is responsible for addition of the Poly-A sequence to the end of an mRNA molecule. Post-transcriptional modification of the 3 ends of eukaryotic mRNA occurs prior to splicing and outside the nucleus The addition of a Poly-A tail on the end of a transcript happens because of the transcription of the Poly-T signal from the corresponding gene. identical to the requirement for DNA replication. triphosphates. This is in contrast to DNA replication, where primer is required at initiation. RNA polymerase requires a primer to initiate the assembly of nucleotide triphosphates. This is RNA polymerase does not require primer to initiate the process of assembly of nucleotideExplanation / Answer
Post-transcriptional modification of the 3'ends of eukaryotic mRNA occurs prior to splicing, inside the nucleus. It is true. In prokaryotic cells no modification is necessary, it takes place only in eukaryotic cells, that too inside the nucleus.
Post-transcriptional modification of 3' ends of eukaryotic mRNA is known as polyadenylation. It is true. Because upto200 adenine ribonucleotides are added to the 3'end of eukaryotic mRNA as a part of post-transcriptional modification.
The molecule poly-A polymerase is responsible for addition of poly-A sequence to the end of an mRNA sequence. It is true, because the enzyme poly A polymerase adds adenine ribonucleotides upto 200 in number to the end of an mRNA molecule.
RNA Polymerase doesn't require a primer to initiate the process of assembly of nucleotide triphosphates, whereas in DNA replication a primer is required. This is true, because DNA polymerase can't add deoxyribonucleotides directly to a template DNA without adding them to a preexisting stretch of polynucleotide sequence. Hence a primer is always required for DNA polymerase in order to initiate the process of DNA replication, whereas an RNA polymerase doesn't require to initiate transcription.
Post-transcriptional modification of the 3'ends of eukaryotic mRNA occurs prior to splicing and outside the nucleus. This statement is false, because post-transcriptional modification occurs before splicing only, but not outside the nucleus, instead it occurs inside the nucleus.
The addition of a poly A tail on the end of a transcript occurs because of the transcription of the poly-T signal from the corresponding gene. This statement is false, because no gene has a continuous poly-T end signal. Poly-A tail is added to add more stability to the mRNA.
RNA polymerase requires a primer to initiate the assembly of nucleotide triphosphates, which is identical to the requirement of DNA replication. This is false statement as RNA Polymerase doesn't require any primer.
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