2. You purchase a labrador retriever from a breeder and find that since the age

Question

2. You purchase a labrador retriever from a breeder and find that since the age of 6 months, he has begun to do a quadruple back flip every time he sees food. You are very excited and go back to the breeder hoping to purchase another dog with the same phenotype. The breeder said this phenotype is exceedingly rare but he occasionally gets dogs like this and does not know why. He has a newborn pup and offers to sel him to you for $10,000. He allows you to take a look at the breeding history. pregnant ewborm, Pwp Your doj You hypothesize that the trait could be autosomal recessive or X-linked recessive. a) (3 points) In the case of autosomal recessive transmission, what is the probability that the newborn pup will have the trait? b) (3 points) In the case of X -linked recessive transmission, what is the probability that the newborn pup will have the trait? c) (8 points) The breeder also has another litter of puppies coming as shown on the pedigree. He offers to sell the entire litter to you for $50,000. You do an ultrasound on the pregnant female and determine that there will be four pups. You estimate that a dog with the quadruple flip trait would be worth about $40,000. If transmission is autosomal recessive, is it a better deal to buy the pending litter or buy the single newborn pup? What about if the transmission is X-linked recessive? Why do you think so? Explain and show your work.

Explanation / Answer

A. If there is autosomal recessive trait then there will be 25% chance that the newborn puppy has the same phenotype.

B. If there is recessive x-linked trait then there is 50 % chance for the newborn pup to have the phenotype.

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