s What process is used to identify possible ribozyme substrates? a. DNA SELEX DN
ID: 187709 • Letter: S
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s What process is used to identify possible ribozyme substrates? a. DNA SELEX DNA BLAST e. RISC d. RNA SELEX e GENE What property must a ribozyme possess in order to be used in clinical medicine? a. stability and resistance to degradation c. expression within a diseased cell only d. be able to be delivered to the correct location e. all of the above 114. u What is a riboswitch? a. an mRNA sequence that binds directly to an effector molecule to control the translation of the mRNA into protein b. an enzyme that converts ribozymes into deoxyribozymes e. the effector molecule responsible for translational control of a particular mRNA d. an RNA molecule that switches between being translated into protein or being a ribozyme e. none of the above 15. Which of the following is not an example of a n effector molecule for ribo- switches? a. some cyclic mononucleotides b. oligonucleotides c. metal ions d. some proteins e. antisense RNAs 16. Which RNA is incorrectly paired with its function? a. snRNA -RNA processing b. circRNA - transcriptional regulation c. piRNA-RNA processing d. Xist -chromosomal structure e. IncRNA transcriptional regulation 17. Which of the following helps replicate telomeres? a. snoRNA b. Xist c. TERC d. gRNA e. circRNA 18. In Drosophila, two non-coding RNAs called roX1 and roX2 are used to a. double the expression of X chromosomal genes in males b. inhibit the expression of one X chromosome in females c. inactivate X chromosomal gene expression in males d. regulate the replication of sex chromosomes in males and female. 19. What is the role of the alpha (a) antisense form in PTEN expression? a. Anneals over complementary areas to prevent degradation. b. Attraction of miRNAs to promote PTEN mRNA degradation. (Continued)Explanation / Answer
12) RNA Selex is a powerful method to determine the binding site of a protein on RNA.
13) all of the above.
14) A riboswitch is generally present at the 5' UTR region of a mRNA that directly binds to its effector molecules(ligand) to control the translation of that mRNA into protein.
15) oligonucleotide
16)piRNA play its role in gene silencing, especially the silencing of transposons.
17)TERC (Telomerase RNA component) helps replicate telomeres.
18)rox1 and rox2 are required for dosage compensation in male Drosophila by hyper transcribing the X chromosome.
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