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Hyperkalemic periodic paralysis (HYPP) is a genetic disorder in horses character

ID: 187737 • Letter: H

Question

Hyperkalemic periodic paralysis (HYPP) is a genetic disorder in horses characterized by occasional uncontrolled shaking and paralysis. The symptom is caused by a dysfunctional sodium channel that is unable to properly regulate sodium levels in the blood. A cross between an HYPP-affected stallion and an HYPP-affected mare produces a foal that suffers from HYPP. The following year, a cross between the same two parents produces a healthy foal unaffected by HYPP. a. Is HYPP a dominant or a recessive condition? b. What are the genotypes of the parents?

Explanation / Answer

a. Here HYPP is a recessive condition. Actually they have recessive allele to express the trait. Here one parent can be heterozygous and other parent is homozygous.

b. So the genotype of the parent are PP(homozygous Dominant HYPP AFFECTED)

Pp( Heterozygous carrier)

Pp( HETEROZYGOUS CARRIER),

pp(Homozygous Recessive, , healthy foal unaffected by HYPP)