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Assume a typical neuron with equilibrium potential for potassium, EK = -80mV and

ID: 188242 • Letter: A

Question

Assume a typical neuron with equilibrium potential for potassium, EK = -80mV and a resting potential of -65mV. How would the resting membrane potential (Vm) of this neuron change if it were immersed in a bath containing a concentration of K+ 20% greater than normal K+ concentration?

A. Vm would not change because K+ does not affect resting membrane potential

B. Vm would be more negative than -65 mV

C. Vm would change to about +60 mV

D. Vm would be more positive than -65 mV

E. Vm would change to about -80 mV

Explanation / Answer

Answer: D. Vm would be more positive than -65 mV

When exposed to high levels of extracellular K+ ions the chemical gradient reverses, Positively charged K+ ions move inside the cell increasing the voltage towards more positive, effectively depolarizing the cell.

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