following compound: 10. Interpreting Ramachandran Plots Examine the two proteins

Question

following compound: 10. Interpreting Ramachandran Plots Examine the two proteins labeled (a) and (b) below. Which of the two Ra- machandran plots, labeled (c) and (d), is more likely to be derived from which protein? Why? [Sources: (a) PDB ID 1GWY, J. M. Mancheno et al., Structure 11:1319, 2003. (b) PDB ID 1A6M, J. Vojtechovsky et al., Biophys. J. 772153, 19991 CH2 CH3 02 CH NH-C- COOH O2N +180 120 60 0 60 120 180 +180 180 0 0(degrees) +180 120 60 0 60 120 180 +180 0 180 © w.H. Freeman Publishers-ISBN 9781319140%gegrees)

Explanation / Answer

Here C option is showing B sheet structure in the dark region between +120 and +180. Means option b matches to option a.

While option b and d showing right handed alpha helix structure of an amino acid in the dark region according to ramachandran plot.

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