organism to your testing (see graph below). For each possible mechanism listed b
ID: 190050 • Letter: O
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organism to your testing (see graph below). For each possible mechanism listed below, please wher each of these organisms would be affected by this antibiotic if it worked by the listed mechanism explain your answers. (2 points each; 4 points total) is a likely target according to the data, and why or why not. Please 100 90 80 70 60 50 e 40 30 20 10 0 Bacillus subtilis 70S Acanthamoeba castellanii 705 Acanthamoeba cstlni Pyroboculum cerophilum75 nen -old ca eropki a. Inhibitipe the formation oftetrapeptides in peptidoglycan (2 points r Tle a eu castelehi is very low 8. Using these same 3 organisms shown above, you test out 3 new antibiotics that are known to function by inhibiting the function of the 70S ribosome. Antibiotic A kills only B subtilis. Antibiotic B kills both A. castellani and P aerophilum. Antibiotic C kills B. subtilis, A. castellanii and P. aerophilum. Assuming that the antibiotic can penetrate any of these cell types equally well and reach the location of the ribosomes, please explain how this can be possible when all 3 antibiotic drugs inhibit 70S ribosome function. (2 points)Explanation / Answer
Antibiotics= A, B, C Inhibit the function on 70S ribosomes
Antibiotic A- Can act only on Prokaryotes . B. subtilis is prokaryote have 70S ribosome. eg. tetracycline
Antibiotic B- Can act on both Prokaryotes and eukaryotes . B. subtilis is prokaryotes and Acanthamoeba castellanii is single cell eukaryote have 70S and 80S ribosome.eg hygromycine B
Antibiotic C- Can act on Prokaryotes and eukaryotes and Archara . B. subtilis is prokaryotes and Acanthamoeba castellanii is single cell eukaryote and Pyrobaculum aerophilum is archaea have 70S ribosome. eg- fusidic acid, pactamycin
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